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TZID:America/Chicago
BEGIN:DAYLIGHT
DTSTART:20250309T030000
TZOFFSETFROM:-0600
TZOFFSETTO:-0500
RRULE:FREQ=YEARLY;BYDAY=2SU;BYMONTH=3
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DTSTART:20241103T010000
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BEGIN:VEVENT
DTSTAMP;TZID=America/Chicago:20260409T100203
UID:196210@calendar.wisc.edu
DTSTART;TZID=America/Chicago:20241108T120000
DTEND;TZID=America/Chicago:20241108T130000
DESCRIPTION:Non-proportional Hazards: What\, Me Worry?. Dr. Wittes will dis
 cuss some of the common causes of non-proportionality in time to event cli
 nical trials\, focusing on three classes of reasons: 1 - experimental inte
 rvention leads to early harm or late benefit\; 2. the study population at 
 randomization is at non-constant risk and the time to event tends to be sh
 orter in those of higher risk status\; 3. a new standard of care introduce
 d during the trial\, or a pandemic that affects the two treatment groups d
 ifferently.\n\nCONTACT: junjie.hu@wisc.edu\n\nURL: https://biostat.wisc.ed
 u/seminars\n\nONLINE: https://uwmadison.zoom.us/j/99879638765
LOCATION:Auditorium\, Genetics-Biotechnology Center Building  (Also offered
  online)
SUMMARY:Biostatistics and Medical Informatics Department Seminar - DeMets L
 ecture with Janet Wittes
URL;VALUE=URI:https://biostat.wisc.edu/seminars
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